House

House (Hugh Laurie) attempts to solve a medical mystery behind bars on the Season Premiere. Odette Annable ("Breaking In") joins the Cast as a Series Regular. Jaleel White ("Family Matters") and Michael Paré ("Eddie and the Cruisers") Guest Star.

House returns to familiar territory. Charlyne Yi ("Paper Heart") Joins Cast as Series Regular.

Altruism is a curious symptom. Olivia Wilde and Wentworth Miller ("Prison Break") guest star.

A business decision calls loyalty into question. Michael Nouri ("Damages") guest stars.

A shocking confession compromises a patient's life. Jamie Bamber ("Battlestar Galactica") Guest Stars.

Parenting decisions leave a lasting impact. John Scurti ("Rescue Me") Guest Stars.

An angst-ridden 14-year-old girl's condition mysteriously worsens; House (Hugh Laurie) gets into trouble after insisting on solving the mystery of why a 4-year-old girl died; and Park (Charlyne Yi) tries to get Chase (Jesse Spencer) to admit why he has become obsessed with grooming.

A patient's paranoia has an adverse medical effect.

When an Alzheimer's patient taking part in a drug trial inexplicably begins vomiting violently and throwing temper tantrums, a deep-seated conflict with his dutiful wife begins to manifest itself. Meanwhile, House (Hugh Laurie) and Foreman (Omar Epps) butt heads; and Wilson (Robert Sean Leonard) treats a patient who claims to be in a chaste marriage.

A teen Jane Doe needs a surgery that requires adult consent. House (Hugh Laurie) and Adams (Odette Annable) debate whether to call Social Services, but then her mother shows up. Meanwhile, Taub (Peter Jacobson) can't connect with his infant daughters; and House threatens to exploit Foreman's (Omar Epps) relationship with a married woman.

Following a violent incident involving a patient, House (Hugh Laurie) and the team are placed under review by neurology chief Walter Cofield (guest star Jeffrey Wright), a onetime mentor of Foreman's (Omar Epps). The doctors must recount the details of the incident to him, and Cofield must weigh the team's unconventional brand of collaboration against their life-saving skills.

Chase takes on a patient, Moira (guest star Julie Mond), who is a cloistered nun on the verge of making her life-changing vows, and through the treatment process, he and Moira form a unique connection that tests their faith and reason.

A marriage counselor (Jake Weber) collapses during a speaking engagement, when it is discovered that, in addition to vision and liver problems, his low testosterone levels are affecting his marriage and career for the better. Meanwhile, House's wife returns to prepare House for their meeting with Homeland Security for her green card, as the team vies for a position as House's second-in-command.

House and the team battle to save a successful, independent blind man who is struck down by a mysterious illness, just prior to him asking for his girlfriend's hand in marriage.

A soldier (Arlen Escarpeta) returning from overseas, accused of treason after releasing a video showing soldiers killing civilians, collapses and is taken to Princeton-Plainsboro. He soon refuses treatment until he has the opportunity to explain his decision to the masses. Meanwhile, Adams and the team believe House is seriously ill.

House and the team take the case of a minor league hockey player (Greg Finley) who began coughing up blood after a fight on the ice. Meanwhile, House reveals to Wilson that he might have an 11 year-old son, and Park moves in with Chase after a fight with her mother.

A man (Kevin Christy) is admitted to the hospital when he begins crying blood, but the team suspects a neurological component when they meet his "girlfriend"- a very lifelike sex doll with whom he's fallen in love, and he also admits why. Meanwhile, House confronts his insecurities when his hooker/companion decides to leave him.

The team analyzes the significance of dreams.

The team treats a young girl with a genetic condition. Episode directed by Hugh Laurie.

When the hospital's coroner (Jamie Elman) begins slicing his own scalp open, he is admitted but will only accept medical care personally decided on by House. However, House is unreachable as he and Wilson embark on a journey for Wilson to forget his upcoming scan and let loose. Meanwhile, a conversation with the patient leads Chase to re-evaluate his career.

A patient's illness has its roots in the body and mind.

In the emotional series finale, directed by series creator and executive producer David Shore, treating a drug addict patient (guest star James LeGros, "Mildred Pierce") results in House examining his life, his future and his own personal demons.

A one-hour retrospective special that will look back at this groundbreaking, seminal series and feature interviews with the series' stars and producers, special original content and other surprises.