In an old B&B in a sleepy seaside town, there lives a vampire, a werewolf and a ghost determined to live a quiet, human life. But lurking in every corner of society there are vampires ready to rid the world of its humanity. It's not easy protecting a newborn child from marauding vampires when you're a ghost and a couple of werewolves, but this is what our heroes must do - whatever the cost.

Hal, Leo, and Pearl – another vampire, werewolf, and ghost – turn up at the house on a pilgrimage to visit the baby Saviour, in the hope that she might save dying Leo. Annie is convinced that her ward has the power to do so, but Tom isn’t so sure. Tom’s not best pleased at having plummy vampire Hal (Damien Molony) in the house, either.

Hal is unaccustomed to modern life, having kept himself sheltered from society to avoid the risk of killing. So when Annie and Tom tell him he needs to get a job, he’s filled with dread. Whilst faced with the horror of working in the café with Tom, Hal is tempted by vampire Fergus to come back to the vampire fold as their new leader.

Annie, Hal, and Tom are like a ring of steel protecting baby Eve, so when Kirby (James Lance), a ghost from the 1970s calls at the house, they’re immediately suspicious. Kirby wins them over with his feckless personality and proof that he’s been sent by Nina to help look after the baby.

Episode Five sees the return of Series Three’s teenage vampire Adam (Craig Roberts). Adam is madly in love with no-nonsense head teacher Yvonne (Selina Griffiths), much to the dismay of our heroes. They’re on the run from the press, who see the relationship as a scandal. Since vampires can’t be pictured on camera, the housemates are concerned about Adam getting photographed.

Romance is in the air for Tom in Episode Six when Allison, a geeky teen werewolf, turns up looking for help. Somebody seems intent on revealing werewolves to the world and she wants to get to the bottom of the matter. In a bid to impress Allison, Tom leads her to the web-savvy vampire, Cutler. Cutler is delighted to see more werewolves on the scene and soon finds use for his new friends.

Tensions run high when Cutler takes Tom firmly under his wing. He’s got big plans for Tom – together they’re going to be history-makers. Hal’s wicked past catches up with him and he finds himself led down a path of temptation. Having succumbed to drinking blood, Hal’s second date with Alex doesn’t exactly go to plan. Meanwhile, Annie is called to Purgatory by the mysterious woman from the future.

The Old Ones have arrived and are intent on taking over the world by force. Cutler has other plans, but when they go awry, his revenge on his own kind is plotted. Annie is conflicted and upset as she comes to terms with the fact that, in order to save the world, she’s been tasked with the most difficult decision of her afterlife.