Cat (Bea Alonzo) is in love with her best friend Wacky (Dingdong Dantes) who works as a morning show host. When Cat gets stranded in the rain, David (Enrique Gil) drives by and is instantly mesmerized by her beauty and takes a video that goes viral. Wacky helps David look for the girl, not knowing that it is his best friend Cat. "She's the One" is a Filipino romantic comedy film by Star Cinema.