Totally Spies!

Redheads start vanishing worldwide after visiting the new Cutting Edge Hair Salons. Sam has Clover and Alex dress up as redheads to investigate the salon, but they are turned down. However, Clover is invited back as her blonde hair attracts the shop owner's assistants.

Noting that Jerry is acting strangely, the spies discover that an evil scientist named Dr. V has taken over Jerry's brain. Dr. V is microscopic in size, so the girls get into a vehicle and shrink themselves to micro-size to search for the doctor inside Jerry's body before he uses Jerry to take over WOOHP and the world. In the subplot, Alex tries to evade having to dissect a live frog.

Sudden spikes in global warming and ozone holes start occurring at the same time that a new suntan lotion labeled "Sun Block SPF 10,000" goes on sale. Just a coincidence or a somewhat apocalyptic marketing plan? The girls try to find the culprit fast since the Earth is getting hotter and hotter by the minute. In the subplot, Clover wants David to choose her as his painting model.

The Spies investigate the hottest new pop band, Teensicle, when one of the band members mysteriously disappears. When he resurfaces seemingly safe and sound, the spies detect strange changes in his personality and talent. It turns out a group of washed up pop stars named Boy Candy are stealing the current pop stars' faces in order to revive their has-been careers.

Looking for Mother's Day gifts for their mothers, Clover, Sam and Alex find a flier about a special offer at a spa. But after they get there, they notice that their moms are not behaving normally when they make ruthless attempts to do them in. They find out that their nemesis Tim Scam has escaped from prison and has turned their mothers into cold-blooded assassins and plans to abduct them

Animals at the Beijing Zoo start developing human intelligence and anthropomorphic features while humans regress into a state of animalistic retardation. The Spies ponder over how to thwart the scheme hatched by a mad scientist named Dr. Fox who has been mixing human and animal DNA. Clover falls prey to his undertaking, becoming part beagle.

The Spies go camping in a remote Saskatchewan forest in order to investigate a garbled but alarming message from a TV news crew who vanished while looking into reports of the disappearance of dozens of loggers, farmers, and hikers in the area. While one reporter was trapped in a cocoon and also been put in a coma thanks to the rescue by Sam.

A school ski trip turns into a stressful situation when the girls have to share a room with Mandy, something that even Jerry cannot fix. Each of the girls then is thrown into an accident that nearly kills them; they suspect Mandy to be the cause until Jerry informs them that an old villain Dr. Gelee has escaped from prison. Gelee mistakenly kidnaps Mandy, leaving the girls to rescue her.

For absolutely no reason at all, the strange "Arrow through the Heart" dating booths appear out of nowhere and all the girls in Beverly Hills, Sam & Alex included, are addicted to their very hunky boyfriends in the process. But Clover suspects something is wrong, and decides to get to the bottom of it, even without Jerry's help.

A high-tech toy manufacturer uses military microchips to make his action figures more realistic. The chips unintentionally cause his toys to become bent on world domination. In the subplot, Clover has a new boy toy who caters to her every whim.