History's Greatest Mysteries

One of World War II's greatest unsolved mysteries: an incomparable work of art worth half a billion dollars, lost without a trace. Where is the famed Amber Room?

A powerful union activist disappears from a Detroit suburb. 45 years later, it remains one of the most notorious missing person cases of all time.

An infamous Cold War cold case: nine hikers found mutilated on a remote mountain slope. For over 60 years, authorities and amateurs have been trying to figure out what happened.

As the Cold War ramps up, a man is found dead within miles of a nuclear testing site on a tranquil Australian beach. Who is the Somerton Beach man, and how did he die?

After a series of dark and ominous events, an unassuming family home on Long Island becomes the most notorious house in America.

A definitive look at Sir Ernest Shackleton's historic and ill-fated 1914 Antarctic expedition resulting in the loss of his highly revered ship.

It's a treasure coveted by everyone from Roman Emperors to Adolf Hitler, and may be the world's most sought-after relic. But what is the Holy Grail?

One of the most chilling aviation mysteries in modern day: a Boeing 777, carrying 239 people, vanishes over the Indian Ocean. What really happened to Malaysia Flight 370?

One of the most chilling aviation mysteries in modern day: a Boeing 777, carrying 239 people, vanishes over the Indian Ocean. What really happened to Malaysia Flight 370?

It's a treasure coveted by everyone from Roman Emperors to Adolf Hitler, and may be the world's most sought-after relic. But what is the Holy Grail?

On Christmas morning, 1945, five siblings vanish from their family home in West Virginia during a raging fire. The devastated family spends the rest of their lives trying to find out what happened.

It might be the world's most mysterious book: a medieval manuscript filled with unidentifiable drawings and a complex secret language. What is the Voynich Manuscript?

A spree of gruesome murders shocks Victorian England-and the world. The homicidal maniac responsible remains a mystery. Can history's most notorious serial killer ever be identified?

When the infant son of an aviation legend is snatched from his crib at home, it ignites a media firestorm. The culprit is brought to justice. But did they get the right man?

A series of unexplained deaths near Chicago in 1982 starts a nationwide panic. The victims are connected by one frightening detail: cyanide-tainted capsules of Tylenol.