Uday (Siddharth) is a rich and spoiled brat and Sandhya (Shamili) is a lone responsible girl. Uday falls in love with Sandhya at the very first sight and strives hard to impress her. When everything is going well, Uday learns that Sandhya is suffering from cancer and her days are numbered. The rest of Oye! is about how Uday helps Sandhya realise all her wishes.