History's Greatest Mysteries

One of World War II's greatest unsolved mysteries: an incomparable work of art worth half a billion dollars, lost without a trace. Where is the famed Amber Room?

A powerful union activist disappears from a Detroit suburb. 45 years later, it remains one of the most notorious missing person cases of all time.

An infamous Cold War cold case: nine hikers found mutilated on a remote mountain slope. For over 60 years, authorities and amateurs have been trying to figure out what happened.

As the Cold War ramps up, a man is found dead within miles of a nuclear testing site on a tranquil Australian beach. Who is the Somerton Beach man, and how did he die?

After a series of dark and ominous events, an unassuming family home on Long Island becomes the most notorious house in America.

A definitive look at Sir Ernest Shackleton's historic and ill-fated 1914 Antarctic expedition resulting in the loss of his highly revered ship.

It's a treasure coveted by everyone from Roman Emperors to Adolf Hitler, and may be the world's most sought-after relic. But what is the Holy Grail?

One of the most chilling aviation mysteries in modern day: a Boeing 777, carrying 239 people, vanishes over the Indian Ocean. What really happened to Malaysia Flight 370?

On Christmas morning, 1945, five siblings vanish from their family home in West Virginia during a raging fire. The devastated family spends the rest of their lives trying to find out what happened.

It might be the world's most mysterious book: a medieval manuscript filled with unidentifiable drawings and a complex secret language. What is the Voynich Manuscript?

A spree of gruesome murders shocks Victorian England-and the world. The homicidal maniac responsible remains a mystery. Can history's most notorious serial killer ever be identified?

When the infant son of an aviation legend is snatched from his crib at home, it ignites a media firestorm. The culprit is brought to justice. But did they get the right man?

A series of unexplained deaths near Chicago in 1982 starts a nationwide panic. The victims are connected by one frightening detail: cyanide-tainted capsules of Tylenol.