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A fire chief's wife is found burnt to death in her home. An autopsy reveals the cause of death was not the fire but a gunshot to the head, shocking a small Louisiana town. This arson turned homicide leaves a killer to be found.

A gifted Philadelphia graduate student is found murdered in her bed. The hunt for her killer forces police to re-evaluate a series of unsolved crimes, turning the city upside down.

When an 11-year-old girl vanishes while waiting for an ice cream truck, it's clear she's been abducted. The search for her leads to a trail of suspects, making it the largest missing child investigation in Arizona history.

A 12-year-old girl goes missing on her way to school in Oregon City, OR. The police investigation offers little in the way of leads until the unthinkable happens -- a second girl disappears.

A Florida man goes hunting on the morning of his anniversary. When he fails to return home that afternoon, an all-out search commences. It's only the beginning of a sordid mystery that will take close to 20 years to solve.

A popular teen goes for a run around her hometown in Maine. Days later her savagely beaten body is found. What happened remains a mystery for years, until her mother intervenes and forces police to re-examine the case.

When three women from three different decades meet their death or go missing under mysterious circumstances, authorities are forced to examine the one thing they had in common: they all fell in love with the same man.

A celebratory night turns deadly for a Texas family when they are gunned down at home. One man's ability to forgive is tested as he fights to save the criminal mastermind from the death penalty.

In 1969 race riots in York, PA, claim the life of an African-American mother and a white police officer. Their deaths are largely forgotten until 30 years later, when their cold cases are reopened, revealing the city's dark past.

A woman goes missing in the fall of 1977. The police finally uncover the horrific truth about the woman's whereabouts. Capturing the killer proves even more difficult, as he manages to always stay one step ahead of the law.

Panic overwhelms the Bay Area when bags full of body parts start appearing all over the region in the summer of 2000. Investigators follow the trail of grisly clues, leading to the discovery of a secret cult.

A 19-year-old woman is brutally assaulted outside of Desert Hot Springs, CA. Miraculously she escapes but lives in constant fear that he will find her again one day. What the victim doesn't realize is she survived a serial killer.

A haven for higher learning is turned upside down when two students are murdered in their dorm rooms. Investigators dive into campus life and reveal a serial killer in the making.

A popular 19-year-old girl is set on fire and left to burn alive. Her last words lead detectives down a road of dead ends, and the case goes cold until a special agent taps into her location data and finds a suspect.

A woman found murdered in Los Angeles in 1969. For decades police investigate, hoping to put a name to the face and find her killer. The one lead that comes up over and over? Charles Manson and the Manson family.